An 8-year-old Huntsville girl who was injured in a head-on collision that killed her mother and brother was pronounced dead today at Primary Children's Medical Center, but remains on life support for organ donation.

"In tragedy there is an opportunity for greatness," Nellene Howard, Esther Howard's aunt, said during a press conference. "Our children have been our greatest blessing and now they have the opportunity to be a blessing to others."

Esther's two surviving siblings remain in intensive care at Primary Children's.

Janine Howard, 40, and Matthew Howard, 11, were killed on impact in the 3:30 p.m. crash on U.S. 89 between 2200 North and Sunset Drive in Layton.

Caleb Howard, 7, remained hospitalized Friday in critical condition, and Rachel Howard, 13, was listed in stable condition.

Sgt. John Holden said the Howards' car was traveling south on U.S. 89 when a pickup truck heading north suddenly veered into opposite lane of travel.

Police did not release the name of the truck driver as citations and charges are pending. The driver remains hospitalized at Ogden Regional Hospital, police said.